Early allergen introduction is supported by clinical studies
Medical guidelines are now consistent with early
Leading health organizations including the American Academy of Pediatrics (AAP), the National Institutes of Health (NIH), and the American Academy of Allergy, Asthma, and Immunology (AAAAI) have updated their guidelines for the early introduction of peanut, and are in the process of developing new guidelines for egg and other allergenic foods.
Want to learn more about these clinical studies and updated guidelines? It's all here in our education section.
L E A P study
in peanut allergiesLearning Early About Peanut allergyStarting at 4 months of ageDuration of exposure 4 years6g peanut protein per week
Over 600 children between 4 and 11 months of age at high risk for peanut allergy were randomized to either consume or avoid peanut until age 5 in order to compare the incidence of peanut allergy between the two groups.
Children in the peanut consumption arm of the trial ate a peanut-containing snack-food at least three times each week, while children in the peanut avoidance arm did not ingest peanut-containing foods.
E A T study
in peanut, egg, & milk allergiesEnquiring About ToleranceStarting at 3 months of ageDuration of exposure 3 months3g peanut, egg, milk protein per week
1,300 3-month-old babies that represented the general population (no risk factors) were randomized to either consume or avoid peanut, cooked egg, cow's milk, sesame, white fish, and wheat until age 3, in order to measure early introduction's effectiveness on various potential food allergens. Measurement occurred every 3 months.
43% of parents could not adhere to study protocol; top reasons cited were reduced maternal quality of life and difficulty getting the child to eat the foods consistently.
Children in the early introduction arm of the trial ate each food 3 times each week, while children in the avoidance arm did not eat any of the foods.
P E T I T study
in egg allergiesPrevention of Egg Allergy in High-Risk Infants with EczemaStarting at 4 months of ageDuration of exposure 6 months0.88g egg protein per week
147 children between 4 and 5 months of age with atopic dermatitis (eczema) were randomized to either consume or avoid egg for 6 months, in order to determine if step-wise (low to high dose) early allergen introduction is an effective method of lowering the risk of food allergy development. Throughout the study, mothers continued to breastfeed.
Children in the egg consumption arm of the trial ate egg powder mixed with squash 3 times a week, while the placebo group avoided egg entirely.
Hear what doctors say
"I recommend early and sustained allergen introduction for all babies starting at 4-6 months of age, based on the current guidelines."
Jonathan Spergel, M.D., Board-certified Pediatric Allergist, Head of Allergy at Children’s Hospital of Philadelphia
“Babies should use this product for at least 6 months or until they are eating these foods regularly”
Katie Marks-Cogan, M.D., Co-founder, Ready, Set, Food!, Board-certified Allergist
“I strongly recommend early allergen introduction to every parent, starting when their baby is 4 months of age.”
Andrew Matthew, M.D., Board-certified Pediatrician, Chair of Pediatrics at Los Robles Hospital
"All babies should start early and sustained allergen introduction at 4-6 months"
Gary Rachelefsky, M.D., Board-certified Pediatric Allergist, Former President of the American Academy of Allergy, Asthma, and Immunology (AAAAI)
“Early allergen introduction is the most important thing parents need to do for the future health of their baby”
Robert Hamilton, M.D., Board-certified Pediatrician
“Parents can feel comfortable that the evidence supports early allergen introduction”
Steven Czinn, M.D., Chief of Pediatrics at the University of Maryland Medical Center